3,5-二叔丁基水楊醛

3,5-Di-tert-butylsalicylaldehyde
	IUPAC名; 3,5-Di-tert-butyl-2-hydroxybenzaldehyde
識別
CAS號	37942-07-7
PubChem	688023
ChemSpider	599518
SMILES	O=Cc1cc(cc(c1O)C(C)(C)C)C(C)(C)C;
InChI	InChI=1S/C15H22O2/c1-14(2,3)11-7-10(9-16)13(17)12(8-11)15(4,5)6/h7-9,17H,1-6H3;
性質
化學式	C15H22O2
摩爾質量	234.33 g·mol−1
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

3,5-二叔丁基水楊醛（英語：3,5-Di-tert-butylsalicylaldehyde，也稱為3,5-二叔丁基-2-羥基苯甲醛，3,5-Di-tert-butyl-2-hydroxybenzaldehyde），分子式C₁₅H₂₂O₂，常溫常壓下為淡黃色固體，是合成Salen配體的前體^[1]。

它可通過2,4-二叔丁基苯酚的達夫反應製備：^[1]

2,4-二叔丁基苯酚和多聚甲醛在三乙胺和氯化鎂的存在下於四氫呋喃中反應，也能得到3,5-二叔丁基水楊醛。^[2]

參考文獻[編輯]

^ ^1.0 ^1.1 Jay F. Larrow and Eric N. Jacobsen (2004). "(R,R)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino Manganese(III) Chloride, A Highly Enantioselective Epoxidation Catalyst". Org. Synth.; Coll. Vol. 10: 96.
^ Yingying Ren, Qishun Yu, Chengrong Lu, and Bei Zhao. Enantioselective Michael Addition of Malononitrile to Unsaturated Ketones Catalyzed by Rare-Earth Metal Amides RE[N(SiMe3)2]3 with Phenoxy-Functionalized TsDPEN Ligands. J. Org. Chem. 2023, 88, 18, 13205–13213. doi:10.1021/acs.joc.3c01435.

外部連結[編輯]

[jacobsen-1] 1.0 ^1.1 Jay F. Larrow and Eric N. Jacobsen (2004). "(R,R)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino Manganese(III) Chloride, A Highly Enantioselective Epoxidation Catalyst". Org. Synth.; Coll. Vol. 10: 96.

[2] Yingying Ren, Qishun Yu, Chengrong Lu, and Bei Zhao. Enantioselective Michael Addition of Malononitrile to Unsaturated Ketones Catalyzed by Rare-Earth Metal Amides RE[N(SiMe3)2]3 with Phenoxy-Functionalized TsDPEN Ligands. J. Org. Chem. 2023, 88, 18, 13205–13213. doi:10.1021/acs.joc.3c01435.

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